Products

  • BioPerine® is a patented standardized extract obtained from black pepper, containing not less than 95% piperine
  • A clinically proven bioavailability enhancer for nutrients1

Bioavailability

  • Bioavailability is “the quantity of a substance, either nutrient, drug, or toxicant, that effectively reaches the target cells where it modifies, for good or bad, their metabolism and consequently their fate”.1

1 Basu, T.K.: The influence of drugs with particular reference to aspirin on bioavailability of Vitamin C; in Counsell, Hornig, Vitamin C, pp.273-281 (Applied Science Publishers, Barking 1981)


A natural bioavailability enhancer for nutrients
  • Herbal extracts
    • e.g. curcumin, Boswellin®, ashwagandha, Gingko biloba, capsaicin
  • Water-soluble vitamins
    • e.g. vitamin B1, vitamin B2, niacinamide, vitamin B6, vitamin B12, folic acid, vitamin C
  • Fat-soluble vitamins
    • e.g. vitamin A, vitamin D, vitamin E, vitamin K
  • Antioxidants
    • e.g. vitamin A, vitamin C, vitamin E, alpha-carotene, transbeta-carotene, beta-cryptoxanthin, lycopene, lutein/zeaxanthin, pine bark bioflavanoids complex, germanium, selenium, zinc
  • Amino Acids
    • e.g. lysine, isoleucine, leucine, threonoine, valine, tryptophan, phenylalanine, methionine
  • Minerals
    • e.g calcium, iron, zinc, vanadium, selenium, chromium, iodine, potassium, manganese, copper, magnesium

Possible mechanisms for increased nutrient bioavailability using BioPerine®

  • Non specific mechanisms promoting rapid absorption of nutrients
    • Increases blood supply to the GI tract
  • Water-soluble vitamins
    • Increases emulsifying content of the gut
  • Fat-soluble vitamins
    • Increases active nutrient transport

Average daily consumption of piperine with black pepper vs. daily requirements for BioPerine®

Average daily consumption of piperine with black pepper vs. daily requirements for BioPerine®

*Estimated daily consumption of piperine with black pepper
Data based on doctoral thesis by Shore Scott Kindell, Drexel University, 1984
** Estimated daily consumption of BioPerine®


“Once the window of opportunity for piperine-nutrient interaction has been missed nutrient absorption is not enhanced”

-Nutrition Science News, March 1996


BioPerine® increased the absorption of co-administered beta-carotene in human volunteers

Average daily consumption of piperine with black pepper vs. daily requirements for BioPerine®

*Estimated daily consumption of piperine with black pepper
Data based on doctoral thesis by Shore Scott Kindell, Drexel University, 1984
** Estimated daily consumption of BioPerine®


Effect of BioPerine® on serum selenium levels during a 6 week supplementation trial in human volunteers

Average daily consumption of piperine with black pepper vs. daily requirements for BioPerine®

Efficacy of BioPerine® (5 mg) on the bioavailability of Vitamin B6 absorption in human volunteers

Efficacy of BioPerine® (5 mg) on the bioavailability of Vitamin B6 absorption in human volunteers

Effect of BioPerine® on serum CoQ10 levels during a 21 day supplementation trial

Effect of BioPerine® on serum CoQ10 levels during a 21 day supplementation trial

Effect of BioPerine® on Serum Concentrations of Curcumin in Human Volunteers

Effect of BioPerine® on Serum Concentrations of
Curcumin in Human Volunteers

Multivitamin Bioavailability (+/- Piperine)

  • Piperine supplementation significantly increased the bioavailability of vitamin C and vitamin E from the standard multivitamin formulation
  • The bioavailability of vitamin B6, B12, Betacarotene, or calcium was improved with piperine supplementation

    HEADQUARTERS

  • Unit no.1200, 2nd Floor,
    Citiview Building
    12 Mac Dinh Chi Street
    Dakao Ward, District 1
    Hochiminh City 700000
    Vietnam

  • +84(28) 3930 0341
  • +84(28) 3930 0342
  • info@sabinsa.vn

CERTIFICATES

Certificate Logos Certificate Logos
Certificate Logos Certificate Logos

CONTACT US