Curcuma longa (Turmeric)

Active components


Nutraceutical applications


Anti-inflammatory support

Immune support

Plant part used



U.S. PATENT #5,861,415 (1999)

INTERNATIONAL PATENT: European Patent # EP0839037 (2002)

Beneficial Effects of Curcuminoids

  • Curcumin C3 Complex® is an effective "Bioprotectant”, antioxidant quenching free radicals and also preventing their formation1
  • Curcumin has been shown to be a COX-2 (Cyclooxygenase-2) inhibitor1
  • Unlike conventional non steroidal anti-inflammatory drugs (NSAIDs), curcuminoids do not cause gastrointestinal side effects or ulcers
  • Curcuminoids support a healthy immune system1
  • Prevent connective tissue break down through inhibiting destructive enzymes2

Nutraceutical Applications of Curcuminoids

  • Antioxidant support
  • Alzheimer’s disease/dementia
  • Cardiovascular support
  • Immune support/Anti-tumor/Anticancer effects, Anti-inflammatory support
  • Wound healing
    • For example: Rheumatoid arthritis, postoperative inflammation, colorectal cancer, bladder cancer, oral leucoplakia, psoriasis, antiviral effects

Pharmacology & Clinical Trials

  1. Curcumin/Piperine - IND study approved: IND# 61,872
    • Food & Drug Administration Office of Drug Evaluation I, Division of Oncology Drug Products
  2. The effects of Curcuminoids on aberrant crypt foci in the human colon: IND# 51,685
    • UMDNJ- Robert Wood Johnson Medical School, New Jersey Cancer Institute
  3. Pilot study of curcuminoids with or without BioPerine® in patients with multiple myeloma: IND# 67,963
    • MD Anderson Cancer Center, University of Texas
  4. Prevention and intervention ofAlzheimer's disease with curcuminoids: - University of California, Los Angeles
  5. Curcuminoids in patients with Lichen planus: IND#65,700/S-000 - University of California
  6. Phase IIa prevention study of C3 Complex® curcuminoids in women at increased risk for breast cancer
    • MD Anderson Cancer Center, University of Texas
  7. The clinical and laboratory effects of topical curcuminoids in patients with normal skin and with dysplastic and benign nevi
    • National Cancer Institute
  8. Phase II prevention study with C3 Complex® in patients with colorectal cancer stage I-III
    • Lincoln Medical and Mental Health Center, Bronx, NY
  9. Phase I trial of C3 Complex® and precooperative patients with locally advanced esophageal or gastroesophageal carcinoma
    • MD Anderson Cancer Center, University of Texas
  10. Metabolic studies and chemopreventive studies -University of Leicester, UK


1 -

2 - Liacini, A. et al. Matrix Biol. 2002 Apr;21(3):251-62


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